Myth: “Men1 and Men2 are the only genetic causes of Cushingâs”

FACT: This is a Myth. More current research has explored multiple etiologies of Cushing’s. It was once thought that heredity had no influence on the development of Cushing’s Syndrome/Disease and our knowledge was once limited in this sense. Researchers have done more work in terms of exploring genetic factors in the onset of this disease. *~Robin Ess (Cushing’s educator and advocate)
The following causes for Cushing’s have all been explored:
1. Men 1
2. Men2
3. FIPA
4. CAH/BAH
5. PRKAR1A(protein kinase,cAMP-dependent, regulatory, type I, ? gene)
http://www.medscape.org/viewarticle/564106_2
6.(PDE11A)
http://www.medscape.org/viewarticle/564106_4
http://www.medscape.org/viewarticle/564106_6
7.PRKACA
http://www.nature.com/nrendo/journal/v10/n8/pdf/nrendo.2014.89.pdf?WT.ec_id=NRENDO-201408
http://www.ncbi.nlm.nih.gov/pubmed/24700472
http://www.nature.com/ng/journal/v46/n6/full/ng.2956.html
https://www.genomeweb.com/sequencing/exome-sequencing-study-narrows-new-cushings-syndrome-gene-culprit
8.ARMC5
http://www.sciencedaily.com/releases/2014/10/141013090455.htm
http://www.nejm.org/doi/full/10.1056/NEJMoa1304603
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