Study of SPI-62 in subjects with ACTH-dependent Cushing’s syndrome caused by a non-adrenal tumor

This is a randomized, placebo-controlled, study of SPI-62 in subjects with ACTH-dependent Cushing’s syndrome caused by a non-adrenal tumor.

Subjects will receive each of the following 2 treatments for 24 weeks: SPI-62 and matching placebo with the option of long-term extension.

Apply for this study at https://www.cancer.gov/research/participate/clinical-trials-search/v?id=NCI-2023-02543

 

What Do *You* Think? Only One Urine Test for Cushing’s?

I sure had way more than one urine test, and lots of blood and more but that was a long time ago.  What are your thoughts on this?


Warning sign: Being very overweight can be a sign of Cushing’s syndrome, a hormonal disorder that is often caused by tumors of the pituitary gland. Image:

Being very overweight, having a moon face and a bull neck are signs of Cushing’s syndrome. It is caused by an excess of the hormone cortisol. Researchers from Giessen and Munich have taken advantage of this to make diagnosis easier.

A special form of obesity, Cushing’s syndrome, is now easier to diagnose. Researchers at the University of Giessen and the Ludwig Maximilian University of Munich have shown that this metabolic disease can be detected using a urine test.

Typically, people with Cushing’s syndrome are very overweight, have a noticeably round face and a bull neck. This is caused by an excess of the stress hormone cortisol, which belongs to the steroid group. The researchers examined urine from Cushing’s patients at the Munich University Hospital using gas chromatography and mass spectrometry. This made it possible to determine the hormone status that is characteristic of the disease. The urine test is simple and provides quick results. So far, several blood samples and sometimes even a hospital stay have been necessary to detect the syndrome.

From https://www.breakinglatest.news/health/cushings-syndrome-can-be-detected-with-a-urine-test/

Dr. Theodore Friedman Will Be Giving a Brief Update on Growth Hormone Replacement

Dr. Theodore Friedman will be giving a brief update on growth hormone replacement, then answer your questions about endocrine issues.
He can not give specific medical advice and this does not replace making an appointment, but he can answer your questions on any endocrine topic including:
  • Cushing’s disease
  • Adrenal insufficiency/Addison’s
  • Hypothyroidism/Hashimoto’s
  • Graves’ Disease
  • Menopause
  • PCOS
  • Growth hormone deficiency
  • Hypopituitarism

For both existing and potential patients.

Sunday • January 21, 2024  • 6 PM PST

Please join using the links below
https://www.facebook.com/goodhormonehealth/  or Via Zoom Click to join the meeting
meeting ID 420 968 7343, passcode 111116
Slides will be available on the day of the talk here.

For more information, email us at mail@goodhormonehealth.com